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Dean Smith’s men were deep in a relegation battle before the hiatus, having lost five consecutive matches in all competitions and four in the league.
Indeed, they are 11/5 (3.20) outsiders with bet365 to move out of the bottom three by pulling off a morale-boosting win in their comeback game.
The Blades’ only two league away defeats in 13 outings so far this campaign have come at Liverpool and Manchester City, and they are 5/4 (2.25) favourites to extend this impressive form by coming out on top here.
The guests let slip a three-goal lead to draw 3-3 in last season’s Championship meeting at this ground, and you can get odds of 12/5 (3.40) on this game also finishing up all square.
John McGinn is back in contention after returning from the ankle injury that has kept him out since December, although Tom Heaton and Wesley remain long-term absentees.
Enda Stevens was the only injury concern prior to the league’s suspension but is now available and rejoins a fully fit squad.
Having let in just 12 goals in 13 away league matches so far this season - a superior record to anyone but leaders Liverpool - it is hard to see Chris Wilder’s men surrendering a three-goal lead as they did in last season’s trip to Villa Park.
In fact, they have only conceded more than two goals in one match so far this season, albeit scoring three or more just twice themselves.
With the Villans having failed to score in their last two league fixtures, odds of 8/11 (1.73) are surely too good to pass up on under 2.5 goals being scored for Sheffield United’s 12th league match in 13.
Odds correct at the time of writing. Please gamble responsibly.