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Arsenal lost Granit Xhaka andPablo Mari to injuries within the first 25 minutes of their Premier League return against Manchester City.
Xhaka was injured just seven minutes into Wednesday's match, which was held at a wet and rainy Etihad Stadium.
The midfielder went over on his ankle as he chased back in midfield, and after being assessed by Arsenal's medical team, he was deemed unfit to continue.
Xhaka's injury forced Mikel Arteta into a change just moments into the club's first match in three months, with the Spanish manager turning to Dani Ceballos to replace his injured midfielder.
More to follow.