Please Wait . . .
With barely three minutes on the clock, the Spaniard hesitated on the ball and ended up kicking a clearance straight into the onrushing Dominic Calvert-Lewin.
The in-form Toffees forward deflected the ball into the net to give the home side an early lead at Goodison Park.
His error left him as a target for fans' ire and amusement, with plenty pointing out it wasn't his first mistake of the season.
The incident attracted focus on De Gea's future both for his club and at international level.
Dean Henderson has impressed on loan at Sheffield United this season, while Spain face a goalkeeping dilemma ahead of Euro 2020 with De Gea out of form and Kepa Arrizabalaga out of the team at Chelsea.